A Review of Moisturizing Additives for Atopic Dermatitis

Atopic dermatitis, the most common form of eczema, is a chronic, relapsing inflammatory skin condition that occurs with dry skin, persistent itching, and scaly lesions. This debilitating significantly compromises patient’s quality life due to intractable itching other associated factors such as disfigurement, sleeping disturbances, social stigmatization from visible The treatment mainstay atopic dermatitis involves applying topical glucocorticosteroids calcineurin inhibitors, combined regular use moisturizers. However, conventional treatments possess certain degree adverse effects, which raised concerns among patients resulting in non-adherence treatment. Hence, modern moisturizers improve barrier repair function great value. One approaches includes incorporating bioactive ingredients clinically proven therapeutic benefits into dermocosmetics emollient. current evidence suggests these emollients aid improvement alleviate inflammation, pruritus xerosis. We carried out critical comprehensive narrative review literature. Studies trials focusing on include phytochemicals, natural moisturizing factors, essential fatty acids, endocannabinoids, antioxidants were identified by searching electronic databases (PubMed MEDLINE). introduce knowledge roles alleviating symptoms dermatitis. then further summarize science rationale active medical device for treating Finally, we highlight limitations future perspectives cosmeceutical research